Clobetasone butyrate
CAS No. 25122-57-0
Clobetasone butyrate ( —— )
产品货号. M24140 CAS No. 25122-57-0
丁酸氯倍他松可用于缓解皮质类固醇反应性皮肤病,包括特应性皮炎和牛皮癣。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ¥616 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Clobetasone butyrate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述丁酸氯倍他松可用于缓解皮质类固醇反应性皮肤病,包括特应性皮炎和牛皮癣。
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产品描述Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic?dermatitis and psoriasis. Clobetasone butyrate is a synthetic glucocorticoid. It has topical anti-inflammatory activity especially in skin .
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体外实验——
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体内实验Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy. Animal Model:Large white domestic pigDosage:0.5% application on the skin Administration:7 weeks Result:Caused moderate to slight atrophy.
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同义词——
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通路Others
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靶点Other Targets
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受体glucocorticoid
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研究领域——
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适应症——
化学信息
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CAS Number25122-57-0
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分子量478.98
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分子式C26H32ClFO5
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纯度>98% (HPLC)
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溶解度DMSO:240 mg/mL (501.06 mM)
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SMILESC[C@@]1(C2)[C@](C(CCl)=O)(OC(CCC)=O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)C2=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Munro DD, et al. Clobetasone?butyrate, a?new?topical?corticosteroid:?clinical?activity?and?effects?on?pituitary-adrenal?axis?function?and?model?of?epidermal?atrophy.
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